diff --git a/include/boost/system/detail/config.hpp b/include/boost/system/detail/config.hpp
index 26e0a4c..ad958bc 100644
--- a/include/boost/system/detail/config.hpp
+++ b/include/boost/system/detail/config.hpp
@@ -13,7 +13,7 @@
 
 // BOOST_SYSTEM_HAS_SYSTEM_ERROR
 
-#if !defined(BOOST_NO_CXX11_HDR_SYSTEM_ERROR) && !defined(BOOST_NO_CXX11_HDR_ATOMIC)
+#if !defined(BOOST_NO_CXX11_HDR_SYSTEM_ERROR) && !defined(BOOST_NO_CXX11_HDR_ATOMIC) && !defined(BOOST_NO_CXX11_HDR_MUTEX)
 # define BOOST_SYSTEM_HAS_SYSTEM_ERROR
 #endif