diff --git a/HISTORY.rst b/HISTORY.rst
index a2bf6ad8..7b124df6 100644
--- a/HISTORY.rst
+++ b/HISTORY.rst
@@ -6,6 +6,11 @@ Release Notes
 PlatformIO Core 4
 -----------------
 
+4.3.4 (2020-??-??)
+~~~~~~~~~~~~~~~~~~
+
+* Automatically build ``contrib-pysite`` package on a target machine when pre-built package is not compatible (`issue #3482 <https://github.com/platformio/platformio-core/issues/3482>`_)
+
 4.3.3 (2020-04-28)
 ~~~~~~~~~~~~~~~~~~
 
diff --git a/platformio/commands/home/command.py b/platformio/commands/home/command.py
index 1eaad046..32d28063 100644
--- a/platformio/commands/home/command.py
+++ b/platformio/commands/home/command.py
@@ -22,11 +22,7 @@ import click
 
 from platformio import exception
 from platformio.compat import WINDOWS
-from platformio.managers.core import (
-    build_contrib_pysite_deps,
-    get_core_package_dir,
-    inject_contrib_pysite,
-)
+from platformio.managers.core import get_core_package_dir, inject_contrib_pysite
 
 
 @click.command("home", short_help="PIO Home")
@@ -55,12 +51,7 @@ def cli(port, host, no_open, shutdown_timeout):
     # import contrib modules
     inject_contrib_pysite()
 
-    try:
-        from autobahn.twisted.resource import WebSocketResource
-    except:  # pylint: disable=bare-except
-        build_contrib_pysite_deps(get_core_package_dir("contrib-pysite"))
-        from autobahn.twisted.resource import WebSocketResource
-
+    from autobahn.twisted.resource import WebSocketResource
     from twisted.internet import reactor
     from twisted.web import server
     from twisted.internet.error import CannotListenError
diff --git a/platformio/commands/remote/command.py b/platformio/commands/remote/command.py
index d4a1cc34..f9e24c29 100644
--- a/platformio/commands/remote/command.py
+++ b/platformio/commands/remote/command.py
@@ -44,7 +44,7 @@ def cli(ctx, agent):
             "https://docs.platformio.org/page/core/installation.html"
         )
     ctx.obj = agent
-    inject_contrib_pysite()
+    inject_contrib_pysite(verify_openssl=True)
 
 
 @cli.group("agent", short_help="Start a new agent or list active")
diff --git a/platformio/managers/core.py b/platformio/managers/core.py
index cb6ad31c..64b4a8b6 100644
--- a/platformio/managers/core.py
+++ b/platformio/managers/core.py
@@ -100,15 +100,26 @@ def update_core_packages(only_check=False, silent=False):
     return True
 
 
-def inject_contrib_pysite():
-    from site import addsitedir  # pylint: disable=import-outside-toplevel
+def inject_contrib_pysite(verify_openssl=False):
+    # pylint: disable=import-outside-toplevel
+    from site import addsitedir
 
     contrib_pysite_dir = get_core_package_dir("contrib-pysite")
     if contrib_pysite_dir in sys.path:
-        return
+        return True
     addsitedir(contrib_pysite_dir)
     sys.path.insert(0, contrib_pysite_dir)
 
+    if not verify_openssl:
+        return True
+
+    try:
+        from OpenSSL import SSL  # pylint: disable=import-error,unused-import
+    except:  # pylint: disable=bare-except
+        build_contrib_pysite_deps(get_core_package_dir("contrib-pysite"))
+
+    return True
+
 
 def build_contrib_pysite_deps(target_dir):
     if os.path.isdir(target_dir):
@@ -146,11 +157,11 @@ def get_contrib_pysite_deps():
     sys_type = util.get_systype()
     py_version = "%d%d" % (sys.version_info.major, sys.version_info.minor)
 
-    twisted_version = "19.7.0"
+    twisted_version = "19.10.0" if PY2 else "20.3.0"
     result = [
         "twisted == %s" % twisted_version,
-        "autobahn == 19.10.1",
-        "json-rpc == 1.12.1",
+        "autobahn == 20.4.3",
+        "json-rpc == 1.13.0",
     ]
 
     # twisted[tls], see setup.py for %twisted_version%
@@ -159,12 +170,12 @@ def get_contrib_pysite_deps():
     )
 
     # zeroconf
-    if sys.version_info.major < 3:
+    if PY2:
         result.append(
             "https://github.com/ivankravets/python-zeroconf/" "archive/pio-py27.zip"
         )
     else:
-        result.append("zeroconf == 0.23.0")
+        result.append("zeroconf == 0.26.0")
 
     if "windows" in sys_type:
         result.append("pypiwin32 == 223")