diff --git a/src/plugins/android/androidconfigurations.cpp b/src/plugins/android/androidconfigurations.cpp
index 87f2d8b60e6..d8714476ed6 100644
--- a/src/plugins/android/androidconfigurations.cpp
+++ b/src/plugins/android/androidconfigurations.cpp
@@ -870,6 +870,7 @@ FilePath AndroidConfig::qtLiveApkPath() const
 ///////////////////////////////////
 void AndroidConfigurations::setConfig(const AndroidConfig &devConfigs)
 {
+    emit m_instance->aboutToUpdate();
     m_instance->m_config = devConfigs;
 
     m_instance->save();
diff --git a/src/plugins/android/androidconfigurations.h b/src/plugins/android/androidconfigurations.h
index aba533fc279..c19e68dbf44 100644
--- a/src/plugins/android/androidconfigurations.h
+++ b/src/plugins/android/androidconfigurations.h
@@ -209,6 +209,7 @@ public:
     static QProcessEnvironment toolsEnvironment(const AndroidConfig &config);
 
 signals:
+    void aboutToUpdate();
     void updated();
 
 private:
diff --git a/src/plugins/android/androidqtversion.cpp b/src/plugins/android/androidqtversion.cpp
index ff8606a1e0a..48aeab8e543 100644
--- a/src/plugins/android/androidqtversion.cpp
+++ b/src/plugins/android/androidqtversion.cpp
@@ -49,7 +49,12 @@ namespace Internal {
 
 AndroidQtVersion::AndroidQtVersion()
     : QtSupport::BaseQtVersion()
+    , m_guard(std::make_unique<QObject>())
 {
+    QObject::connect(AndroidConfigurations::instance(),
+                     &AndroidConfigurations::aboutToUpdate,
+                     m_guard.get(),
+                     [this] { resetCache(); });
 }
 
 bool AndroidQtVersion::isValid() const
diff --git a/src/plugins/android/androidqtversion.h b/src/plugins/android/androidqtversion.h
index c9869608191..5098f533565 100644
--- a/src/plugins/android/androidqtversion.h
+++ b/src/plugins/android/androidqtversion.h
@@ -58,6 +58,7 @@ public:
 protected:
     void parseMkSpec(ProFileEvaluator *) const override;
 private:
+    std::unique_ptr<QObject> m_guard;
     mutable QStringList m_androidAbis;
     mutable int m_minNdk = -1;
 };
diff --git a/src/plugins/qtsupport/baseqtversion.cpp b/src/plugins/qtsupport/baseqtversion.cpp
index 13bab8c6f9c..95f65b12eab 100644
--- a/src/plugins/qtsupport/baseqtversion.cpp
+++ b/src/plugins/qtsupport/baseqtversion.cpp
@@ -2169,6 +2169,11 @@ Abis BaseQtVersion::qtAbisFromLibrary(const FilePathList &coreLibraries)
     return res;
 }
 
+void BaseQtVersion::resetCache() const
+{
+    d->m_hasQtAbis = false;
+    d->m_mkspecReadUpToDate = false;
+}
 
 // QtVersionFactory
 
diff --git a/src/plugins/qtsupport/baseqtversion.h b/src/plugins/qtsupport/baseqtversion.h
index 8de93f138bc..6d0e13b5cdf 100644
--- a/src/plugins/qtsupport/baseqtversion.h
+++ b/src/plugins/qtsupport/baseqtversion.h
@@ -245,6 +245,8 @@ protected:
     // helper function for desktop and simulator to figure out the supported abis based on the libraries
     static ProjectExplorer::Abis qtAbisFromLibrary(const Utils::FilePathList &coreLibraries);
 
+    void resetCache() const;
+
     void ensureMkSpecParsed() const;
     virtual void parseMkSpec(ProFileEvaluator *) const;