diff --git a/src/libs/qtcreatorcdbext/CMakeLists.txt b/src/libs/qtcreatorcdbext/CMakeLists.txt
index 7bf3bcc9e89..8c95cb400b8 100644
--- a/src/libs/qtcreatorcdbext/CMakeLists.txt
+++ b/src/libs/qtcreatorcdbext/CMakeLists.txt
@@ -75,8 +75,9 @@ if (_library_enabled)
       else()
         set(PythonZipFileName "python${CMAKE_MATCH_4}.zip")
       endif()
+      set(PythonNameWithVersion "${CMAKE_MATCH_3}")
 
-      set(PythonDll "${CMAKE_MATCH_1}/${CMAKE_MATCH_3}${CMAKE_SHARED_LIBRARY_SUFFIX}")
+      set(PythonDll "${CMAKE_MATCH_1}/${PythonNameWithVersion}${CMAKE_SHARED_LIBRARY_SUFFIX}")
       set(PythonExe "${CMAKE_MATCH_1}/python${CMAKE_EXECUTABLE_SUFFIX}")
       set(PythonZip "${CMAKE_MATCH_1}/${PythonZipFileName}")
 
@@ -92,6 +93,76 @@ if (_library_enabled)
     return()
   endif()
 
+  # Support for cross-compilation for arm64 on a x64 system
+  if (MSVC_CXX_ARCHITECTURE_ID MATCHES "^ARM" AND CMAKE_HOST_SYSTEM_PROCESSOR MATCHES "^AMD")
+    find_program(dumpbin_executable dumpbin)
+    find_program(lib_executable lib)
+
+    string(TOLOWER ${MSVC_CXX_ARCHITECTURE_ID} lower_arch_name)
+
+    if (NOT dumpbin_executable OR NOT lib_executable)
+      message(WARNING "Couldn't locate dumpbin.exe or lib.exe executables")
+      return()
+    endif()
+
+    if (Python3_VERSION VERSION_LESS "3.11.0")
+      message(WARNING "Python 3.11.0 needs to be installed. This version is the first version that has arm64 Windows support")
+      return()
+    endif()
+
+    execute_process(
+      COMMAND ${dumpbin_executable} /exports ${PythonDll}
+      OUTPUT_VARIABLE dumpbin_output
+      RESULT_VARIABLE dumpbin_result)
+
+    string(REGEX REPLACE ".*[ \t]+ordinal[ \t]+hint[ \t]+RVA[ \t]+name[\r\n][\r\n]" "" dumpbin_output "${dumpbin_output}")
+    string(REGEX REPLACE "[\r\n][ \t]+Summary[\r\n].*" "" dumpbin_output "${dumpbin_output}")
+    string(REGEX REPLACE "([ \t]+[0-9]+)([ \t]+[a-fA-F0-9]+)([ \t]+[a-fA-F0-9]+)[ \t]+([a-zA-Z0-9_]+)( = [a-zA-Z0-9_]+[\r\n]|[\r\n])" "\\4;" filter_output "${dumpbin_output}")
+
+    string(APPEND pythondef "LIBRARY ${PythonNameWithVersion}\nEXPORTS\n")
+    foreach(var IN LISTS filter_output)
+      if (var)
+        string(APPEND pythondef "${var}\n")
+      endif()
+    endforeach()
+    file(WRITE ${CMAKE_CURRENT_BINARY_DIR}/${PythonNameWithVersion}.def "${pythondef}")
+
+    execute_process(
+      COMMAND ${lib_executable}
+              /def:${CMAKE_CURRENT_BINARY_DIR}/${PythonNameWithVersion}.def
+              /out:${CMAKE_CURRENT_BINARY_DIR}/${PythonNameWithVersion}.lib /machine:${lower_arch_name} /nologo)
+    set(Python3_LIBRARIES "${CMAKE_CURRENT_BINARY_DIR}/${PythonNameWithVersion}.lib")
+
+    if (NOT PythonTargetArchDll AND ENV{PythonTargetArchDll})
+      set(PythonTargetArchDll $ENV{PythonTargetArchDll})
+    endif()
+
+    if (NOT PythonTargetArchDll)
+      set(python_embed_url "https://www.python.org/ftp/python/${Python3_VERSION}/python-${Python3_VERSION}-embed-${lower_arch_name}.zip")
+      message(STATUS "Downloading ${python_embed_url}")
+
+      foreach(retry RANGE 10)
+        file(DOWNLOAD ${python_embed_url} ${CMAKE_CURRENT_BINARY_DIR}/python-embed.zip)
+        file(SIZE ${CMAKE_CURRENT_BINARY_DIR}/python-embed.zip fileSize)
+        if (fileSize GREATER 0)
+          break()
+        endif()
+      endforeach()
+
+      file(MAKE_DIRECTORY ${CMAKE_CURRENT_BINARY_DIR}/python-embed)
+      file(ARCHIVE_EXTRACT INPUT ${CMAKE_CURRENT_BINARY_DIR}/python-embed.zip DESTINATION ${CMAKE_CURRENT_BINARY_DIR}/python-embed)
+
+      set(PythonTargetArchDll ${CMAKE_CURRENT_BINARY_DIR}/python-embed/${PythonNameWithVersion}${CMAKE_SHARED_LIBRARY_SUFFIX})
+    endif()
+
+    if (NOT PythonTargetArchDll)
+      message(WARNING "PythonTargetArchDll CMake parameter or ENV{PythonTargetArchDll} was not configured and the Python runtime cannot be configured")
+      return()
+    endif()
+
+    set(PythonDll "${PythonTargetArchDll}")
+  endif()
+
   extend_qtc_library(qtcreatorcdbext
     DEPENDS "${Python3_LIBRARIES}"
     INCLUDES "${Python3_INCLUDE_DIRS}"