diff --git a/src/plugins/cmakeprojectmanager/cmakebuildconfiguration.cpp b/src/plugins/cmakeprojectmanager/cmakebuildconfiguration.cpp
index 41abdd62431..5faed536865 100644
--- a/src/plugins/cmakeprojectmanager/cmakebuildconfiguration.cpp
+++ b/src/plugins/cmakeprojectmanager/cmakebuildconfiguration.cpp
@@ -40,6 +40,7 @@
 #include <ios/iosconstants.h>
 
 #include <coreplugin/find/itemviewfind.h>
+#include <coreplugin/icore.h>
 
 #include <projectexplorer/buildaspects.h>
 #include <projectexplorer/buildinfo.h>
@@ -58,6 +59,7 @@
 
 #include <utils/algorithm.h>
 #include <utils/categorysortfiltermodel.h>
+#include <utils/checkablemessagebox.h>
 #include <utils/detailswidget.h>
 #include <utils/headerviewstretcher.h>
 #include <utils/infolabel.h>
@@ -190,6 +192,36 @@ CMakeBuildSettingsWidget::CMakeBuildSettingsWidget(CMakeBuildConfiguration *bc)
     aspectWidgetBuilder.finishRow();
     initialCMakeAspect->addToLayout(aspectWidgetBuilder);
     aspectWidgetBuilder.finishRow();
+    auto clearCMakeConfiguration = new QPushButton(tr("Re-configure with Initial Parameters"));
+    connect(clearCMakeConfiguration, &QPushButton::clicked, this, [bc]() {
+        auto *settings = CMakeProjectPlugin::projectTypeSpecificSettings();
+        bool doNotAsk{!settings->askBeforeReConfigureInitialParams()};
+        if (!doNotAsk) {
+            QDialogButtonBox::StandardButton reply = Utils::CheckableMessageBox::question(
+                nullptr,
+                tr("Re-configure with Initial Parameters"),
+                tr("Clear CMake configuration and configure with initial parameters?"),
+                tr("Do not ask again"),
+                &doNotAsk,
+                QDialogButtonBox::Yes | QDialogButtonBox::No,
+                QDialogButtonBox::Yes);
+
+            settings->setAskBeforeReConfigureInitialParams(!doNotAsk);
+            settings->toSettings(Core::ICore::settings());
+
+            if (reply != QDialogButtonBox::Yes) {
+                return;
+            }
+        }
+
+        auto cbc = static_cast<CMakeBuildSystem*>(bc->buildSystem());
+        cbc->clearCMakeCache();
+        if (ProjectExplorerPlugin::saveModifiedFiles())
+            cbc->runCMake();
+    });
+    aspectWidgetBuilder.addItem(LayoutBuilder::LayoutItem(new QLabel("")));
+    aspectWidgetBuilder.addItem(LayoutBuilder::LayoutItem(clearCMakeConfiguration));
+    aspectWidgetBuilder.finishRow();
     auto buildTypeAspect = bc->aspect<BuildTypeAspect>();
     connect(buildTypeAspect, &BaseAspect::changed, this, [this, buildTypeAspect]() {
         if (!m_buildConfiguration->isMultiConfig()) {
diff --git a/src/plugins/cmakeprojectmanager/cmakespecificsettings.cpp b/src/plugins/cmakeprojectmanager/cmakespecificsettings.cpp
index bc95e380bc8..070610fd7d7 100644
--- a/src/plugins/cmakeprojectmanager/cmakespecificsettings.cpp
+++ b/src/plugins/cmakeprojectmanager/cmakespecificsettings.cpp
@@ -33,6 +33,7 @@ static const char SETTINGS_KEY[] = "CMakeSpecificSettings";
 static const char AFTER_ADD_FILE_ACTION_KEY[] = "ProjectPopupSetting";
 static const char NINJA_PATH[] = "NinjaPath";
 static const char PACKAGE_MANAGER_AUTO_SETUP[] = "PackageManagerAutoSetup";
+static const char ASK_RECONFIGURE_INITIAL_PARAMS[] = "AskReConfigureInitialParams";
 }
 
 void CMakeSpecificSettings::fromSettings(QSettings *settings)
@@ -53,6 +54,7 @@ void CMakeSpecificSettings::toSettings(QSettings *settings) const
     settings->beginGroup(QString(SETTINGS_KEY));
     settings->setValue(QString(AFTER_ADD_FILE_ACTION_KEY), static_cast<int>(m_afterAddFileToProjectSetting));
     settings->setValue(QString(PACKAGE_MANAGER_AUTO_SETUP), m_packageManagerAutoSetup);
+    settings->setValue(QString(ASK_RECONFIGURE_INITIAL_PARAMS), m_askBeforeReConfigureInitialParams);
     settings->endGroup();
 }
 }
diff --git a/src/plugins/cmakeprojectmanager/cmakespecificsettings.h b/src/plugins/cmakeprojectmanager/cmakespecificsettings.h
index e4ead416c31..273ae7937e1 100644
--- a/src/plugins/cmakeprojectmanager/cmakespecificsettings.h
+++ b/src/plugins/cmakeprojectmanager/cmakespecificsettings.h
@@ -53,10 +53,13 @@ public:
     void setPackageManagerAutoSetup(bool checked) { m_packageManagerAutoSetup = checked; }
     bool packageManagerAutoSetup() const { return m_packageManagerAutoSetup; }
 
+    bool askBeforeReConfigureInitialParams() const { return m_askBeforeReConfigureInitialParams; }
+    void setAskBeforeReConfigureInitialParams(bool doAsk) { m_askBeforeReConfigureInitialParams = doAsk; }
 private:
     AfterAddFileAction m_afterAddFileToProjectSetting;
     Utils::FilePath m_ninjaPath;
     bool m_packageManagerAutoSetup = true;
+    bool m_askBeforeReConfigureInitialParams = true;
 };
 
 }
diff --git a/src/plugins/cmakeprojectmanager/cmakespecificsettingspage.cpp b/src/plugins/cmakeprojectmanager/cmakespecificsettingspage.cpp
index 9b7c71ca440..9653e32b7cd 100644
--- a/src/plugins/cmakeprojectmanager/cmakespecificsettingspage.cpp
+++ b/src/plugins/cmakeprojectmanager/cmakespecificsettingspage.cpp
@@ -72,6 +72,7 @@ CMakeSpecificSettingWidget::CMakeSpecificSettingWidget(CMakeSpecificSettings *se
     }
 
     m_ui.packageManagerAutoSetup->setChecked(settings->packageManagerAutoSetup());
+    m_ui.askBeforeReConfigureWithInitialParams->setChecked(settings->askBeforeReConfigureInitialParams());
 }
 
 void CMakeSpecificSettingWidget::apply()
@@ -80,6 +81,7 @@ void CMakeSpecificSettingWidget::apply()
     m_settings->setAfterAddFileSetting(popupSetting == -1 ? AfterAddFileAction::ASK_USER
                                                   : static_cast<AfterAddFileAction>(popupSetting));
     m_settings->setPackageManagerAutoSetup(m_ui.packageManagerAutoSetup->isChecked());
+    m_settings->setAskBeforeReConfigureInitialParams(m_ui.askBeforeReConfigureWithInitialParams->isChecked());
     m_settings->toSettings(Core::ICore::settings());
 }
 
diff --git a/src/plugins/cmakeprojectmanager/cmakespecificsettingspage.ui b/src/plugins/cmakeprojectmanager/cmakespecificsettingspage.ui
index 171c6a3246c..b232685974c 100644
--- a/src/plugins/cmakeprojectmanager/cmakespecificsettingspage.ui
+++ b/src/plugins/cmakeprojectmanager/cmakespecificsettingspage.ui
@@ -70,6 +70,13 @@
      </property>
     </widget>
    </item>
+   <item>
+    <widget class="QCheckBox" name="askBeforeReConfigureWithInitialParams">
+     <property name="text">
+      <string>Ask before re-configuring with initial parameters</string>
+     </property>
+    </widget>
+   </item>
    <item>
     <spacer name="verticalSpacer">
      <property name="orientation">