diff --git a/src/plugins/cmakeprojectmanager/cmakebuildconfiguration.cpp b/src/plugins/cmakeprojectmanager/cmakebuildconfiguration.cpp
index d50fcdcedb2..cccc08d4b59 100644
--- a/src/plugins/cmakeprojectmanager/cmakebuildconfiguration.cpp
+++ b/src/plugins/cmakeprojectmanager/cmakebuildconfiguration.cpp
@@ -103,6 +103,8 @@ const char CMAKE_CXX_FLAGS[] = "CMAKE_CXX_FLAGS";
 const char CMAKE_CXX_FLAGS_DEBUG[] = "CMAKE_CXX_FLAGS_DEBUG";
 const char CMAKE_CXX_FLAGS_RELWITHDEBINFO[] = "CMAKE_CXX_FLAGS_RELWITHDEBINFO";
 
+const char VXWORKS_DEVICE_TYPE[] = "VxWorks.Device.Type";
+
 namespace Internal {
 
 class CMakeBuildSettingsWidget : public NamedWidget
@@ -1132,6 +1134,11 @@ static bool isWebAssembly(const Kit *k)
     return DeviceTypeKitAspect::deviceTypeId(k) == WebAssembly::Constants::WEBASSEMBLY_DEVICE_TYPE;
 }
 
+static bool isVxWorks(const Kit *k)
+{
+    return DeviceTypeKitAspect::deviceTypeId(k) == VXWORKS_DEVICE_TYPE;
+}
+
 static bool isQnx(const Kit *k)
 {
     return DeviceTypeKitAspect::deviceTypeId(k) == Qnx::Constants::QNX_QNX_OS_TYPE;
@@ -1556,7 +1563,7 @@ CMakeBuildConfiguration::CMakeBuildConfiguration(Target *target, Id id)
             }
         }
 
-        if (isWebAssembly(k) || isQnx(k) || isWindowsARM64(k)) {
+        if (isWebAssembly(k) || isQnx(k) || isWindowsARM64(k) || isVxWorks(k)) {
             if (qt && qt->qtVersion().majorVersion() >= 6)
                 cmd.addArg(CMAKE_QT6_TOOLCHAIN_FILE_ARG);
         }
diff --git a/src/plugins/qtsupport/baseqtversion.cpp b/src/plugins/qtsupport/baseqtversion.cpp
index 1f3bfe2d404..8102cef7c60 100644
--- a/src/plugins/qtsupport/baseqtversion.cpp
+++ b/src/plugins/qtsupport/baseqtversion.cpp
@@ -2372,6 +2372,7 @@ QtVersion *QtVersionFactory::createQtVersionFromQMakePath
     setup.config = evaluator.values("CONFIG");
     setup.platforms = evaluator.values("QMAKE_PLATFORM"); // It's a list in general.
     setup.isQnx = !evaluator.value("QNX_CPUDIR").isEmpty();
+    setup.mkspec = mkspec.fileName();
 
     for (QtVersionFactory *factory : factories) {
         if (!factory->m_restrictionChecker || factory->m_restrictionChecker(setup)) {
diff --git a/src/plugins/qtsupport/qtversionfactory.h b/src/plugins/qtsupport/qtversionfactory.h
index 2832fe55fbc..d370d146131 100644
--- a/src/plugins/qtsupport/qtversionfactory.h
+++ b/src/plugins/qtsupport/qtversionfactory.h
@@ -38,7 +38,8 @@ protected:
     {
         QStringList platforms;
         QStringList config;
-        bool isQnx = false; // eeks...
+        bool isQnx = false; // eeks
+        QString mkspec;
     };
 
     void setQtVersionCreator(const std::function<QtVersion *()> &creator);