diff --git a/CMakeLists.txt b/CMakeLists.txt
index 55fe1a031..23a5c21c2 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -2056,6 +2056,8 @@ if(WOLFSSL_CLU)
     list(APPEND WOLFSSL_DEFINITIONS "-DHAVE_OID_ENCODING" "-DWOLFSSL_NO_ASN_STRICT" "-DWOLFSSL_ALT_NAMES")
     # Add OPENSSL_ALL definition to ensure OpenSSL compatibility functions are available
     list(APPEND WOLFSSL_DEFINITIONS "-DOPENSSL_ALL")
+    # Remove NO_DES3 from WOLFSSL_DEFINITIONS to ensure DES3 is enabled
+    list(REMOVE_ITEM WOLFSSL_DEFINITIONS "-DNO_DES3")
 endif()
 
 if(WOLFSSL_AESCFB)