diff --git a/homeassistant/config_entries.py b/homeassistant/config_entries.py
index da8e73d9566..712db1940e8 100644
--- a/homeassistant/config_entries.py
+++ b/homeassistant/config_entries.py
@@ -3196,6 +3196,8 @@ class ConfigFlow(ConfigEntryBaseFlow):
             options=options,
         )
         if reload_even_if_entry_is_unchanged or result:
+            if entry.update_listeners:
+                raise ValueError("Cannot update entry with update listeners")
             self.hass.config_entries.async_schedule_reload(entry.entry_id)
         if reason is UNDEFINED:
             reason = "reauth_successful"